Os07g0529600

The rice Os07g0529600 was reported as OsDR8 in 2006 by researchers from China.

Annotated Information

Gene Symbol

• Os07g0529600 <=> FOXRED1, OsDR8, OsXNP

Function

• Silencing of OsDR8 using an RNA interference approach resulted in phenotypic alteration of the plants.
• The transgenic plants with repressed expression of OsDR8 showed reduced resistance or susceptibility to Xanthomonas oryzae pv. oryzae and Magnaporthe grisea causing bacterial blight and blast, which are two of the most devastating diseases in rice worldwide, respectively.

Expression

• The impact of OsDR8 on disease resistance in rice may be through the regulation of expression of other defense-responsive genes and the site of OsDR8 function is on the upstream of the signal transduction pathway. In addition, the accumulation of thiamine may be essential for bacterial blight resistance and blast resistance.

Evolution

• The putative product of OsDR8 was highly homologous to an enzyme involved in the biosynthesis of the thiazole precursor of thiamine.

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Labs working on this gene

National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research

References

Dual function of rice OsDR8 gene in disease resistance and thiamine accumulation, Gongnan Wang, Xinhua Ding, Meng Yuan, Deyun Qiu, Xianghua Li, Caiguo Xu and Shiping Wang, Plant Molecular Biology (2006) 60:437-449.