Os07g0164000
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Contents
Annotated Information
Function
WAF1 is required for the stabilization of small RNAs through methylating the last nucleotide,as is Arabidopsis HEN1. Stabilization of small RNAs by WAF1 is indispensable for rice development,especially for SAM maintenance and leaf morphogenesis governed by the ta-siRNA pathway.
Expression
The expression levels of target genes are not always negatively correlated with the miRNA accumulation levels in waf1.This is typically shown in the expression levels of HD-ZIP IIIgenes in WAF1,none of which showed enhanced expression in spite of the drastic reduction in miR166 accumulation.
Evolution
WAF1 is associated with multiple developmental events via the stabilization of many small RNAs.The phenotypic differences between rice WAF1 and Arabidopsis hen1 suggest that during evolution rice has acquired novel small RNAs and/or target genes that are regulated by WAF1.
Labs working on this gene
This work was supported by Grants-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology of Japan(grant nos. 20248001 to Y.N. and 21027007 to J.-i.I.). Corresponding author:e-mail ajunito@mail.ecc.u-tokyo.ac.jp
References
Masashi Abe;Takanori Yoshikawa;Misuzu Nosaka;Hitoshi Sakakibara;Yutaka Sato;Yasuo Nagato;Jun-ichi Itoh WAVY LEAF1, an Ortholog of Arabidopsis HEN1, Regulates Shoot Development by Maintaining MicroRNA and Trans-Acting Small Interfering RNA Accumulation in Rice Plant Physiology,2010,154(3):1335-1346