Os02g0774300

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The rice Os02g0774300 was reported as mtHsp70 in 2010 [1] by researchers from China.

Annotated Information

Gene Symbol

  • Os02g0774300 <=> mtHsp70,OsmtHsp70

Function

  • mtHsp70 may suppress programmed cell death in rice protoplasts by maintaining mitochondrial Mitochondrial membrane potential and inhibiting the amplification of ROS.

Expression

  • Over-expression of mtHsp70 suppressed heat-and H2O2-induced programmed cell death (PCD) in rice protoplasts, as reflected by higher cell viability, decreased DNA laddering and chromatin condensation.
  • Mitochondrial membrane potential after heat shock was destroyed gradu-

ally in protoplasts, but mtHsp70 over-expression showed higher Mitochondrial membrane potential relative to the vector control cells, and partially inhibited cytochrome c release from mitochondria to cytosol.

  • Heat treatment also significantly increased reactive oxygen species (ROS) generation, a phenomenon not observed in protoplasts over-expressing mtHsp70.

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Labs working on this gene

  • College of Life Science, Nanjing Agricultural University, Nanjing, Jiangsu 210095, China

References

  1. Qi Y, Wang H, Zou Y, Liu C, Liu Y, Wang Y, Zhang W. Over-expression of mitochondrial heat shock protein 70 suppresses programmed cell death in rice. FEBS Lett. 2011 Jan 3;585(1):231-9. doi: 10.1016/j.febslet.2010.11.051. PubMed PMID: 21130768.


Structured Information