Os01g0777300
The rice Os01g0777300 was reported as OsExo1 in 2008 [1] by researchers from Japan.
Contents
Annotated Information
Figure 2. Subcellular localization of the OsEXO1-GFP fusion protein in onion epidermal cells.[1].
Gene Symbol
- Os01g0777300 <=> OsExo1,Exo1
Function
- OsEXO1 is able to substitute for ScEXO1 and ScRAD27 functions.
- Yeast two-hybrid analysis shows that OsEXO1 interacted with rice DNA polymerase k (OsPol k), the 70 kDa subunit b of rice replication protein A (OsRPA70b), and the 32 kDa subunit 1 of rice replication protein A (OsRPA32-1).
- OsEXO1 plays an important role in both cell proliferation and UV-damaged nuclear DNA repair pathway under dark conditions.
Expression
- The transcript of OsEXO1 is highly expressed in meristematic tissues and panicles.
- Inhibition of cell proliferation by removal of sucrose from the medium or by the addition of cell cycle inhibitors decreased OsEXO1 expression.
Subcellular localization
- Subcellular localization analysis showed that OsEXO1-sGFP fusion protein transiently overexpressed in the onion epidermal cells localized to the nucleus.
Labs working on this gene
- Division of Plant Biotechnology, Tissue Engineering Research Center, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
- Section of Plant Biology, University of California, Davis, Davis, CA 95616, USA
- Department of Biological Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
- National Institute for Agro-Environmental Sciences, 3-1-3 Kannondai, Ibaraki 305-8604, Japan
References
- ↑ 1.0 1.1 Furukawa T, Imamura T, Kitamoto HK, Shimada H. Rice exonuclease-1 homologue, OsEXO1, that interacts with DNA polymerase lambda and RPA subunit proteins, is involved in cell proliferation. Plant Mol Biol. 2008 Mar;66(5):519-31. doi: 10.1007/s11103-008-9288-6. Epub 2008 Jan 18. PubMed PMID: 18231866.
